Boranes

Borane complexes are versatile compounds commonly used as regio-, chemo- and stereoselective reducing agents for a variety of functional groups such as aldehydes, ketones, carboxylic acids, amides and olefins. The high yields and simple isolation of the reduced products combined with the high selectivities achieved with borane reagents have made these compounds the preferred reducing agents for a number of applications. 

Chiral Reagents

Callery offers both enantiomers of methyl oxazaborolidine (MeCBS), the famous “Corey Catalyst”, and diisopinocampheylchloroborane (DPC) – two options for the enantioselective reduction of prochiral ketones. DPC is a reagent used in slight molar excess, while MeCBS is used in catalytic quantities along with second, non-chiral, borane source.  

Boranes Dpc
(-)-DPC
Available as: (click for details):

(-)-Diisopinocampheylchloroborane

(-)-Ipc2BCl 

CAS#: 85116-37-6
Boranes Dpc
(+)-DPC
Available as: (click for details):

(+)-Diisopinocampheylchloroborane

(+)-Ipc2BCl 

CAS#: 112246-73-8
Boranes Mecbs
(R)-MeCBS
Available as: (click for details):

(R)-Methyl oxazaborolidine

CAS#: 112022-83-0
Boranes Smecbs
(S)-MeCBS
Available as: (click for details):

(S)-Methyl oxazaborolidine

CAS#: 112022-81-8

Alkylboranes - Free Radical Sources

Alkylboranes are highly versatile products used in various industrial applications such as pharmaceuticals, polymers and more. In organic synthesis, triethylborane (TEB) and methoxydiethylborane (MDEB) have proven especially effective as diastereoselective-directing reagents to produce syn-diols from β-hydroxyketones

Boranes Mdeb
MDEB
Available as: (click for details):
CAS#: 7397-46-8
Boranes Teb
TEB
Available as: (click for details):

Triethylborane

CAS#: 97-94-9
Boranes Teb Dap
TEB-DAP
Available as: (click for details):

Triethylborane-1,3-diaminopropane complex

CAS#: 148861-07-8
Boranes Teb Deta
TEB-DETA
Available as: (click for details):

Triethylborane-diethylenetriamine complex

CAS#: 1187733-83-0
Boranes Tnbb Mopa
TnBB-MOPA
Available as: (click for details):

Tri-n-butylborane-3-methoxy-1-propylamine complex

CAS#: 345269-15-0

Borohydride Reducing Agents

Alkali metal trialkylborohydrides have been used in numerous stereoselective and regioselective reductions. The strongest and least selective reducing is CalSelect® LT , while CalSelect® Na and CalSelect® Li are quite selective and reactive.   Calselect® STAB is a highly chemoselective reagent used in reductive amination reactions.

Boranes Calselect Li
CalSelect® Li
Available as: (click for details):

Lithium tri-sec-butylborohydride

CAS#: 38721-52-7
Boranes Calselect Lt
CalSelect® LT
Available as: (click for details):

Lithium triethylborohydride

CAS#: 22560-16-3
Boranes Calselect Na
CalSelect® Na
Available as: (click for details):

Sodium tri-sec-butylborohydride

CAS#: 67276-04-4
Boranes Calselect Stab
CalSelect® STAB
Available as: (click for details):

Sodium triacetoxyborohydride

CAS#: 56553-60-7

Borane Complexes (BH3 Complexes)

Borane complexes with THF, dimethylsulfide and N,N-diethylaniline, offer a convenient source of “BH3” for selective reduction of a variety of functional groups such as aldehydes, ketones, olefins, carboxylic acids, and amides. Callery’s other amine borane complexes are excellent options for reductions where aqueous, alcoholic or acidic solvents are used.  Other amine borane complexes are available upon request.

Boranes Bthf
BTHF
Available as: (click for details):

Borane-tetrahydrofuran complex

CAS#: 14044-65-6
Boranes Deanb
DEANB
Available as: (click for details):

N, N-Diethylaniline borane

CAS#: 13289-97-9
Boranes Dmsb
DMSB
Available as: (click for details):

Dimethylsulfide borane

CAS#: 13292-87-0
Boranes Pemb
PEMB
Available as: (click for details):

5-Ethyl-2-methylpyridine borane

CAS#: 1006873-58-0
Boranes Teab
TEAB
Available as: (click for details):

Triethylamine borane

CAS#: 1722-26-5

Suzuki Coupling and other Specialty Boron Reagents

Boronic acids and esters have become very important building blocks in organic synthesis in for the Suzuki cross coupling reaction. Callery’s line of reagents for synthesis of Suzuki Coupling partners,  such as PinBH or 9-BBN enable reliable paths to your targeted boronic acids and boronate esters.  If you require custom boron-based reagents/intermediates, please call to discuss your needs. 

Boranes 9Bbn
9-BBN
Available as: (click for details):

9-Borobicyclo-[3.3.1]-nonane

CAS#: 280-64-8 monomer21205-91-4 dimer
Boranes Pinb
PinB
Available as: (click for details):

PinBH

HBPin

CAS#: 25015-63-8
Boranes Tmbx
TMBX
Available as: (click for details):

Trimethoxyboroxin

CAS#: 102-24-9